Polypharmacy in the Elderly Affects Medication Adherence When patients take multiple medications, medication adherence often decreases. It makes sense. Patients need to remember more medications—when to take them, how to take them and even if they’ve taken them. In addition, packaging may be harder to read, understand, or open for elderly patients. All these factors can affect med adherence. A pharmacy consult may show ways to streamline medication to help with adherence, for example, combined medications that reduce the overall number of pills taken. In addition, choosing a pharmacy partner with daily dose packaging improves adherence as well. Read more about how Grane Rx keeps pharmacy SIMPLE and effective to improve med adherence.