At Grane Rx, we’re committed to providing the highest-quality post acute care pharmacy services. As part of that commitment, we share an ongoing series of pharmacy updates from our Chief Clinical Officer, designed to keep you in the know on clinical topics related to long term care pharmacy and PACE pharmacy. Antibiotics are some of the most frequently used medications in inpatient and outpatient settings. Due to their amount of use and tolerability, the major side effects that these medications can cause are not always recognized—the biggest of these would be the toxic side effects on the central nervous system (CNS). The most common CNS side effects are seizures, delirium, confusion, personality changes and ototoxicity. If CNS effects occur and are due to antibiotic therapy, they will typically occur within days of starting treatment.